According to a newly published study of proteins and cells, scientists at the University of Guangzhou Sun Yat-sen, China’s first genetically modified human embryos have created. Rumors have been circulating for some time that this had already been done, but until now, there is no official scientific documentation to back it up was. Today, it’s official.
The researchers called for a strategy to accomplish this feat CRISPR (in simple terms) gene used in genetically inherited disease has been discussed. Enzyme complex procedure CRISPR/Cas9, which binds DNA at specific locations, and involves injecting the fetus with splices. The crux of genes and their various molecules, which effectively neutralizes them before a person is born with a replacement can be programmed. And adult human cells, has been shown in animal embryo technique,But this is the first published study to discuss the human fetus.
HBB gene mutations in a protein called their experiments, the researchers sometimes fatal blood disorder can trigger an encoded tried to edit. To fix it, they CRISPR gene used to modify the molecular makeup – but the method is not 100 percent successful.
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On a couple of the fetus, CRISPR missed its target and the DNA used to edit the wrong category. Test methods used in the 86 embryos, only 71 survived, and only 28 of them are married to successfully DNA – which has been shown to contain many new and unintended genetic material.
This is problematic because the disease appears to be accidental mutations, with the next generation has the potential to impact on the disastrous and unforeseen. In this case, there was no intent to permit the embryo to continue to develop. They have been grown specifically for experiments, and are engineered to stop growing at an early stage. Insert your own moral or ethical interpretation.
The test is groundbreaking, sure – but is not quite ready for prime time yet as the gene editing. “You want to do what normal embryo, you could be close to 100%,” the researcher said Huang Jinjiu. “That’s why we stopped. We still think it’s a very rudimentary.”
Thus, the results are very encouraging, we’re still a few years – if not a full decade – Regatta-style away from genetic engineering.
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